Furthermore, the level of cardiomyogenic differentiation-associated extracellular matrix proteins (collagen I, collagen III, collagen IV, fibronectin, and laminin) in MSCs cultured with graphene supplement is increased
Furthermore, the level of cardiomyogenic differentiation-associated extracellular matrix proteins (collagen I, collagen III, collagen IV, fibronectin, and laminin) in MSCs cultured with graphene supplement is increased. stem cells into osteoblasts, chondrocytes, or adipocytes [95]. The BMP signaling pathway also plays key functions in regulating proliferation, differentiation, and survival of cardiac progenitor cells [96]. The expression of BMP-2 is usually increased after myocardial infarction, not only anti-apoptosis, but also regulating Tmem44 the cardiomyocyte differentiation of cardiac progenitors [97]. By controlling the expression of BMP-2, ES cells could differentiate into cardiomyocytes [98]. A previous study also shows that BMP-2 might differentiate BMSCs into a myocardial cell line. Salvianolic acid B could play a cardioprotective role in ES cell-derived cardiomyocytes in a hypoxia condition. Salvianolic acid B also could regulate the differentiation of…