1H-NMR (400 MHz, CDCl3): 3.78 (s, 6 H), 3.82 (s, 3 H), 6.48 (t, = 2.0 Hz, 1 H), 6.76 (d, = 2.4 Hz, 2 H), 6.98 (d, = 8.8 Hz, 2 H), 7.51 (t, = 7.6 Hz, 1 H), 7.67 (t, = 8.0 Hz, 1 H), 7.96 (s, 1 H), 8.07C8.10 (m, 3 H), 8.25 (d, = 8.0 Hz, 1 H). Hz, 1 H), 7.58 (t, = 7.6 Hz, 1 H), 7.70 (t, = 7.6 Hz, 1 H), 7.78 (s, 1 H), 8.06C8.16 (m, 2 H). 13C-NMR (100 MHz, CDCl3): 20.3, 126.1, 126.1, 126.3, 126.6, 127.6, 128.9, 129.6, 130.0, 130.5, 131.1, 133.9, 136.1, 139.4, 148.4, 160.0. HRMS (ESI, = 8.4 Hz, 2 H), 7.52C7.56 (m, 1 H), 7.67C7.71 (m, Mouse monoclonal to CD19.COC19 reacts with CD19 (B4), a 90 kDa molecule, which is expressed on approximately 5-25% of human peripheral blood lymphocytes. CD19 antigen is present on human B lymphocytes at most sTages of maturation, from the earliest Ig gene rearrangement in pro-B cells to mature cell, as well as malignant B cells, but is lost on maturation to plasma cells. CD19 does not react with T lymphocytes, monocytes and granulocytes. CD19 is a critical signal transduction molecule that regulates B lymphocyte development, activation and differentiation. This clone is cross reactive with non-human primate 1 H), 7.99C8.10 (m, 5 H). 13C-NMR (100 MHz, CDCl3): 122.5, 126.6, 126.7, 127.7, 128.7, 129.1, 130.0, 130.7, 134.8, 136.0, 136.7, 148.7, 155.8. HRMS (ESI, = 8.4 Hz, 1 H), 7.94 (d, = 8.4 Hz, 2 H), 8.04C8.10 (m, 3 H). 13C-NMR (100 MHz, CDCl3): 122.4, 124.5, PFE-360 (PF-06685360) 126.6, 126.7, 127.7, 129.0, 130.1, 130.7, 132.0, 134.8, 137.2, 148.7, 155.9. HRMS (ESI, = 8.4 Hz, 1 H), 7.54C7.58 (m, PFE-360 (PF-06685360) 1 H), 7.69C7.73 (m, 1 H), 7.87C7.90 (m, 1 H), 8.02C8.11 (m, 3 H), 8.21 (d, = 2.0 Hz, 1 H). 13C-NMR (100 MHz, CDCl3): 122.2, 126.4, 126.6, 126.8, 128.0, 129.3, 130.1, 130.8, 130.9, 133.3, 134.1, 135.0, 138.1, 148.6, 154.4. HRMS (ESI, = 1.6, 6.8 Hz, 1 H), 7.40 (dd, = 1.6, 8.4 Hz, 1 H) 7.59 (t, = 7.2 Hz, 1 H), 7.72 (t, = 7.2 Hz, 1 H), 7.97 (t, = 7.6 Hz, 1 H), 8.07C8.14 (m, 3 H). 13C-NMR (100 MHz, CDCl3): 119.8, 120.0, 124.1, 124.2, 125.8, 125.9, 126.7, 126.9, 128.1, 128.2, 128.2, 130.0, 130.7, 132.5, 132.6, 134.4, 148.6, 152.6, 159.1, 161.8. HRMS (ESI, = 8.4 Hz, 1 H), 7.48C7.56 (m, 2 H), 7.64C7.68 (m, 1 H), 7.75 (d, = 2.0 Hz, 1 H), 8.05C8.08 (m, 3 H). 13C-NMR (100 MHz, CDCl3): 55.9, 56.0, 110.2, 111.0, 120.3, 122.5, 126.4, 126.5, 127.1, 129.8, 130.5, 131.0, 134.5, 148.6, 149.4, 150.7, 156.6. HRMS (ESI, = 7.2 Hz, 1 H), 7.69 (t, PFE-360 (PF-06685360) = 7.6 Hz, 1 H), 8.04 (s, 1 H), 8.07C8.10 (m, 2 H). 13C-NMR (100 MHz, CDCl3): 56.3, 60.9, 104.8, 122.7, 126.5, 127.5, 129.9, 130.6, 133.8, 134.6, 139.8, 148.5, 153.6, 156.7. HRMS (ESI, = 7.2 Hz, 1 H), 7.86C7.91 (m, 2 H), 7.96 (s, 1 H), 8.05 (d, = 8.0 Hz, 1 H), 8.19 (dd, = 8.8 Hz, 2 H). 13C-NMR (100 MHz, CDCl3): 125.3, 126.1, 126.6, 126.7, 126.9, 127.0, 127.9, 128.0, 128.5, 129.6, 129.9, 130.8, 131.0, 133.9, 134.4, 137.1, 148.4, 159.1. HRMS (ESI, = 2.8, 5.6 Hz, 2 H), 8.08C8.11 (m, 2 H), 8.22C8.24 (m, 2 H), 8.47 (d, = 0.8 Hz, 1 H). 13C-NMR (100 MHz, CDCl3): 123.0, 124.7, 126.4, 126.6, 126.7, 126.9, 127.3, 127.5, 127.7, 128.7, 128.8, 130.1, 130.6, 133.3, 134.0, 134.6, 135.6, 148.8, 156.9. HRMS (ESI, = 8.8 Hz, 2 H), 7.47 (dd, = 1.6, 8.4 Hz, 1 H), 7.80 (s, 1 H), 7.91 (d, = 8.8 Hz, 1 H), 7.98C8.00 (m, 3 H). 13C-NMR (100 MHz, CDCl3): 21.7, 55.3, 114.2, 122.4, 125.3, 126.2, 128.7, 129.6, 131.1, 132.6, 133.7, 137.2, 147.3, 155.8, 160.9. HRMS (ESI, = 8.4 Hz, 2 H), 7.39C7.44 (m, 1 H), 7.70 (dd, = 2.8, 9.6 Hz, 1 H), 7.99C8.05 (m, 4 H). 13C-NMR (100 MHz, CDCl3): 55.4, 110.2, 110.4, 114.3, 120.5, 120.7, 123.0, 127.2, 127.3, 128.8, 130.6, 132.4, 132.5, 133.3, 133.4, 145.8, 156.1, 156.2, 159.7, 161.2, 162.2. HRMS (ESI, = 8.8 Hz, 2 H), 7.57 (dd, = 2.4, 8.8 Hz, 1 H), 7.94C8.05 (m, 5 H). 13C-NMR (100 MHz, CDCl3): 55.4, 114.3, 123.1, 125.5, 127.0, 128.8, 130.4, 131.4, 131.5, 133.0, 133.1, 147.1, 156.9, 161.3. HRMS (ESI, = 8.8 Hz, 2 H), 7.79 (d, = 8.8 Hz, 1 H), 8.03 (d, = 8.4 Hz, 2 H), 8.10 (d, = PFE-360 (PF-06685360) 8.4 Hz, 2 H), 8.34 (s, 1 H). 13C-NMR (100 MHz, CDCl3): 55.4, 114.4, 123.4, 124.6, 124.7, 125.5, 126.1, 126.1, 129.1, 130.0, 131.0, 135.0, 149.7, 158.6,.